triclosan
CAS No.: 3380-34-5 Formula: C12H7Cl3O2 Molecular Weight: 289.54200
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triclosan

CAS No.: 3380-34-5 Formula: C12H7Cl3O2 Molecular Weight: 289.54200
Suppliers: All (244) China Suppliers (161) Price Available (45) Contractor (16)

Description

Triclosan, similar in its uses and mechanism of action to triclocarban, is an antibacterial and antifungal agent found in consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. Its efficacy as an antimicrobial agent, the risk of bacterial resistance and its possible role in disrupted hormonal development remain controversial. Additional research seeks to understand its potential effects on organisms and environmental health.

Basic Info

Properties

Appearance & Physical State
white to off-white powder
Density
1.49 g/cm3
Boiling Point
344.6ºC at 760 mmHg
Melting Point
56-60ºC
Flash Point
162.2ºC
Stability
Stable. Incompatible with strong oxidizing agents.

Safety Info

RTECS
KO1100000
Hazard Class
9
Safety Statements
S22-S24/25
HS Code
2909500000
WGK Germany
2
Packing Group
III
RIDADR
UN 3077 9/PG 3
Risk Statements
R36/38
Hazard Codes
Xi; N
Signal Word
Warning
Symbol
GHS07, GHS09
Caution Statement
P273; P305 + P351 + P338; P391; P501
Hazard Declaration
H315; H319; H410
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SDS 1.0

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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name
triclosan

1.2 Other means of identification

Product number
-
Other names
TRICLOSAN USP

1.3 Recommended use of the chemical and restrictions on use

Identified uses
For industry use only.
Uses advised against
no data available

1.4 Supplier's details

Company
MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address
Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone
+86(21)64956998
Fax
+86(21)54365166

1.5 Emergency phone number

Emergency phone number
+86-400-6021-666
Service hours
Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P273 Avoid release to the environment.

Response

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

P391 Collect spillage.

Storage

none

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
triclosan
triclosan
3380-34-5
none
100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state
white to off-white powder
Colour
no data available
Odour
no data available
Melting point/ freezing point
-45°C(lit.)
Boiling point or initial boiling point and boiling range
290°C(lit.)
Flammability
no data available
Lower and upper explosion limit / flammability limit
no data available
Flash point
55°C(lit.)
Auto-ignition temperature
no data available
Decomposition temperature
no data available
pH
no data available
Kinematic viscosity
no data available
Solubility
no data available
Partition coefficient n-octanol/water (log value)
no data available
Vapour pressure
no data available
Density and/or relative density
1.49 g/cm3
Relative vapour density
no data available
Particle characteristics
no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

11.Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: no data available
  • Dermal: no data available
  • Skin corrosion/irritation

    no data available

    Serious eye damage/irritation

    no data available

    Respiratory or skin sensitization

    no data available

    Germ cell mutagenicity

    no data available

    Carcinogenicity

    no data available

    Reproductive toxicity

    no data available

    STOT-single exposure

    no data available

    STOT-repeated exposure

    no data available

    Aspiration hazard

    no data available

    12.Ecological information

    12.1 Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available
  • 12.2 Persistence and degradability

    no data available

    12.3 Bioaccumulative potential

    no data available

    12.4 Mobility in soil

    no data available

    12.5 Other adverse effects

    no data available

    13.Disposal considerations

    13.1 Disposal methods

    Product

    The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

    Contaminated packaging

    Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

    14.Transport information

    14.1 UN Number

    ADR/RID: UN3077
    IMDG: UN3077
    IATA: UN3077

    14.2 UN Proper Shipping Name

    ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
    IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
    IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

    14.3 Transport hazard class(es)

    ADR/RID: 9
    IMDG: 9
    IATA: 9

    14.4 Packing group, if applicable

    ADR/RID: III
    IMDG: III
    IATA: III

    14.5 Environmental hazards

    ADR/RID: yes
    IMDG: yes
    IATA: yes

    14.6 Special precautions for user

    no data available

    14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

    no data available

    15.Regulatory information

    15.1 Safety, health and environmental regulations specific for the product in question

    Chemical name Common names and synonyms CAS number EC number
    triclosan
    triclosan
    3380-34-5
    none
    European Inventory of Existing Commercial Chemical Substances (EINECS)
    Listed.
    EC Inventory
    Listed.
    United States Toxic Substances Control Act (TSCA) Inventory
    Listed.
    China Catalog of Hazardous chemicals 2015
    Not Listed.
    New Zealand Inventory of Chemicals (NZIoC)
    Listed.
    Philippines Inventory of Chemicals and Chemical Substances (PICCS)
    Listed.
    Vietnam National Chemical Inventory
    Listed.
    Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)
    Listed.

    16.Other information

    Information on revision

    Creation Date
    Aug 11, 2017
    Revision Date
    Aug 11, 2017

    Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%
  • References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

  • Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
    MSDS Expand
    1H NMR : PredictExpand

    NMR Spectrum 1H NMR : Predict

    Collapse
    Mass spectrum (electron ionization)Expand

    GC Analysis

    Total 1 Documents >>
    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Capillary
    DB-5
    -
    2114.
    temperature ramp
    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Administration onto the skin
    Standard Draize test
    Human
    750 ug/3D (Intermittent)
    -
    Administration onto the skin
    Standard Draize test
    Rodent - rabbit
    10%
    -
    Oral
    LD50 - Lethal dose, 50 percent kill
    Rodent - rat
    3700 mg/kg
    1.Details of toxic effects not reported other than lethal dose value
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